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Search for answers here, from our variety of Frequently Asked Questions and Technical Support topics Propofol-related infusion syndrome ( PRIS ) is a rare but potentially fatal complication in critically ill patients It is generally associated with high propofol doses and or prolonged propofol administration but can occur with lower doses and short exposures 49 Apr 30, 2024 · Propofol-related infusion syndrome (PRIS) is a rare but severe condition associated with the administration of propofol, an anesthetic commonly used for sedation in medical procedures First identified in the 1990s, PRIS can be fatal if not recognized and treated promptly pris ca helppris ca our-plans If PRIS is suspected, propofol should be discontinued and an alterna-tive sedative agent initiated General measures to support cardiac and renal function should be initiated promptly in patients with suspected PRIS Welcome to MagicMail Webmail E-mail Address Password Login Warning: This webmail service requires Javascript! 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